IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin

Autism spectrum disorder (ASD) does not have a distinct pathogenesis or effective treatment. Increasing evidence supports the presence of immune dysfunction and inflammation in the brains of children with ASD. In this report, we present data that gene expression of the antiinflammatory cytokine IL-3...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Tsilioni, Irene, Patel, Arti B., Pantazopoulos, Harry, Berretta, Sabina, Conti, Pio, Leeman, Susan E., Theoharides, Theoharis C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815178/
https://ncbi.nlm.nih.gov/pubmed/31591201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906817116
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