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IL-38 inhibits microglial inflammatory mediators and is decreased in amygdala of children with autism spectrum disorder

Autism spectrum disorder (ASD) is characterized by impaired social interactions and communication. The pathogenesis of ASD is not known, but it involves activation of microglia. We had shown that the peptide neurotensin (NT) is increased in the serum of children with ASD and stimulates cultured adul...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tsilioni, Irene, Pantazopoulos, Harry, Conti, Pio, Leeman, Susan E., Theoharides, Theoharis C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7368277/
https://ncbi.nlm.nih.gov/pubmed/32601180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004666117
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