IL-37 is increased in brains of children with autism spectrum disorder and inhibits human microglia stimulated by neurotensin

Autism spectrum disorder (ASD) does not have a distinct pathogenesis or effective treatment. Increasing evidence supports the presence of immune dysfunction and inflammation in the brains of children with ASD. In this report, we present data that gene expression of the antiinflammatory cytokine IL-3...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tsilioni, Irene, Patel, Arti B., Pantazopoulos, Harry, Berretta, Sabina, Conti, Pio, Leeman, Susan E., Theoharides, Theoharis C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815178/
https://ncbi.nlm.nih.gov/pubmed/31591201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906817116
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