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Human papillomavirus 16 promotes microhomology-mediated end-joining

Squamous cell carcinomas (SCCs) arising from aerodigestive or anogenital epithelium that are associated with the human papillomavirus (HPV) are far more readily cured with radiation therapy than HPV-negative SCCs. The mechanism behind this increased radiosensitivity has been proposed to be secondary...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Leeman, Jonathan E., Li, Yi, Bell, Andrew, Hussain, Suleman S., Majumdar, Rahul, Rong-Mullins, Xiaoqing, Blecua, Pedro, Damerla, Rama, Narang, Himanshi, Ravindran, Pavithran T., Lee, Nancy Y., Riaz, Nadeem, Powell, Simon N., Higginson, Daniel S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815166/
https://ncbi.nlm.nih.gov/pubmed/31591214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906120116
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