Sustained ER stress promotes hyperglycemia by increasing glucagon action through the deubiquitinating enzyme USP14

Endoplasmic reticulum (ER) stress plays an important role in metabolic diseases like obesity and type 2 diabetes mellitus (T2DM), although the underlying mechanisms and regulatory pathways remain to be elucidated. Here, we induced chronic low-grade ER stress in lean mice to levels similar to those i...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Liu, Bin, Zhang, Zhijian, Hu, Yanyun, Lu, Yan, Li, Duanzhuo, Liu, Jie, Liao, Shengjie, Hu, Min, Wang, Yuxing, Zhang, Die, Chen, Yulu, Qian, Qilan, Lv, Xianfeng, Wu, Duojiao, Tan, Minjia, Hu, Cheng, Xiong, Xuelian, Li, Xiaoying
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6815134/
https://ncbi.nlm.nih.gov/pubmed/31594848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1907288116
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars