Chargement en cours...

PROTAC induced-BET protein degradation exhibits potent anti-osteosarcoma activity by triggering apoptosis

Targeting oncogenic proteins for degradation using proteolysis-targeting chimera (PROTAC) recently has drawn increasing attention in the field of cancer research. Bromodomain and extra-terminal (BET) family proteins are newly identified cancer-related epigenetic regulators, which have a role in the...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Shi, Chengcheng, Zhang, Huapeng, Wang, Penglei, Wang, Kai, Xu, Denghui, Wang, Haitao, Yin, Li, Zhang, Shuijun, Zhang, Yi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814818/
https://ncbi.nlm.nih.gov/pubmed/31653826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2022-2
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!