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Targeting BET Proteins With a PROTAC Molecule Elicits Potent Anticancer Activity in HCC Cells
Background and Aim: Bromodomain and extraterminal domain (BET) family proteins are epigenetic regulators involved in human malignances. Targeting BET proteins for degradation using proteolysis-targeting chimera (PROTAC) recently has drawn increasing attention in the field of cancer therapeutics. BET...
שמור ב:
| הוצא לאור ב: | Front Oncol |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6971110/ https://ncbi.nlm.nih.gov/pubmed/31993368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01471 |
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