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Matching Glycosyl Donor Reactivity to Sulfonate Leaving Group Ability Permits S(N)2 Glycosylations

[Image: see text] Here we demonstrate that highly β-selective glycosylation reactions can be achieved when the electronics of a sulfonyl chloride activator and the reactivity of a glycosyl donor hemiacetal are matched. While these reactions are compatible with the acid- and base-sensitive protecting...

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Zhuo, Ming-Hua, Wilbur, David J., Kwan, Eugene E., Bennett, Clay S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2019
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814073/
https://ncbi.nlm.nih.gov/pubmed/31550879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b07022
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