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TNFα Induces Multidrug Resistance-Associated Protein 4 Expression through p38-E2F1-Nrf2 Signaling in Obstructive Cholestasis
PURPOSE: To explore the molecular mechanism of the upregulation of multidrug resistance-associated protein 4 (MRP4) in cholestasis. MATERIALS AND METHODS: The mRNA and protein levels of MRP4 in liver samples from cholestatic patients were determined by quantitative real-time PCR and Western blot. In...
Kaydedildi:
Yayımlandı: | Yonsei Med J |
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Asıl Yazarlar: | , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Yonsei University College of Medicine
2019
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6813138/ https://ncbi.nlm.nih.gov/pubmed/31637886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3349/ymj.2019.60.11.1045 |
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