Canalicular membrane MRP2/ABCC2 internalization is determined by Ezrin Thr567 phosphorylation in human obstructive cholestasis

BACKGROUND & AIMS: Multidrug resistance–associated protein 2 (MRP2) excretes conjugated organic anions including bilirubin and bile acids. Malfunction of MRP2 leads to jaundice in patients. Studies in rodents indicate that Radixin plays a critical role in determining Mrp2 canalicular membrane ex...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Hepatol
Main Authors: Chai, Jin, Cai, Shi-Ying, Liu, Xiaocong, Lian, Wei, Chen, Sheng, Zhang, Liangjun, Feng, Xinchan, Cheng, Ying, He, Xiaochong, He, Yu, Chen, Lei, Wang, Rongquan, Wang, Huaizhi, Boyer, James L., Chen, Wensheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686151/
https://ncbi.nlm.nih.gov/pubmed/26212029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.07.016
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados