A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB

The non-canonical NF-κB signaling cascade is essential for lymphoid organogenesis, B-cell maturation, osteoclast differentiation, and inflammation in mammals(1,2), whereas dysfunction of this system is associated with human diseases, including immunological disorders and cancer(3–6). While controlle...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Liu, Zixu, Mar, Katrina B., Hanners, Natasha W., Perelman, Sofya S., Kanchwala, Mohammed, Xing, Chao, Schoggins, John W., Alto, Neal M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812682/
https://ncbi.nlm.nih.gov/pubmed/30894749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1041-6
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