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Noncanonical NF-κB signaling and the essential kinase NIK modulate crucial features associated with eosinophilic esophagitis pathogenesis

Eosinophilic esophagitis (EoE) is an allergic disease of the esophagus driven by T cell and eosinophil responses to dietary allergens, resulting in chronic mucosal inflammation. Few spontaneous animal models of esophageal eosinophilia exist, with most studies relying on artificial sensitization proc...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Eden, Kristin, Rothschild, Daniel E., McDaniel, Dylan K., Heid, Bettina, Allen, Irving C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5769607/
https://ncbi.nlm.nih.gov/pubmed/29259025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.030767
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