Inhibiting microRNA-144 potentiates Nrf2-dependent antioxidant signaling in RPE and protects against oxidative stress-induced outer retinal degeneration

The retinal pigment epithelium (RPE) is consistently exposed to high levels of pro-oxidant and inflammatory stimuli. As such, under normal conditions the antioxidant machinery in the RPE cell is one of the most efficient in the entire body. However, antioxidant defense mechanisms are often impacted...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Jadeja, Ravirajsinh N., Jones, Malita A., Abdelrahman, Ammar A., Powell, Folami L., Thounaojam, Menaka C., Gutsaeva, Diana, Bartoli, Manuela, Martin, Pamela M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812120/
https://ncbi.nlm.nih.gov/pubmed/31590045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101336
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