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Loss of NAMPT in aging retinal pigment epithelium reduces NAD(+) availability and promotes cellular senescence
Retinal pigment epithelium (RPE) performs numerous functions critical to retinal health and visual function. RPE senescence is a hallmark of aging and degenerative retinal disease development. Here, we evaluated the temporal expression of key nicotinamide adenine dinucleotide (NAD(+))-biosynthetic g...
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| Publicado no: | Aging (Albany NY) |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6046249/ https://ncbi.nlm.nih.gov/pubmed/29905535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101469 |
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