An exploratory randomized-controlled trial of the efficacy of the Src-kinase inhibitor saracatinib as a novel analgesic for cancer-induced bone pain

Pain is a major symptom of bone metastases from advanced cancer and represents a clinical challenge to treat effectively. Basic neurobiology in preclinical animal models implicates enhanced sensory processing in the central nervous system, acting through N-methyl-D-aspartate (NMDA) glutamate recepto...

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Опубликовано в: :J Bone Oncol
Главные авторы: Danson, Sarah, Mulvey, Matthew R, Turner, Lesley, Horsman, Janet, Escott, KJane, Coleman, Robert E, Ahmedzai, Sam H, Bennett, Michael I, Andrew, David
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812043/
https://ncbi.nlm.nih.gov/pubmed/31667062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbo.2019.100261
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