712. Activity of Exebacase (CF-301) Against Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilms on Orthopedic Kirschner Wires

BACKGROUND: Orthopedic foreign body-associated infection can be difficult to treat due to the formation of biofilms protecting microorganisms from both antimicrobials and the immune system. Exebacase (EXE) is a phage-derived lysin which acts as a direct lytic agent by hydrolyzing the peptidoglycan c...

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Vydáno v:Open Forum Infect Dis
Hlavní autoři: Karau, Melissa J, Schmidt-Malan, Suzannah, Mandrekar, Jayawant, Lehoux, Dario, Schuch, Raymond, Cassino, Cara, Patel, Robin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6811060/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.780
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