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Postantibiotic and Sub-MIC Effects of Exebacase (Lysin CF-301) Enhance Antimicrobial Activity against Staphylococcus aureus

CF-301 (exebacase) is a recombinantly produced bacteriophage-derived lysin (cell wall hydrolase) and is the first agent of this class to enter clinical development in the United States for treating bacteremia including endocarditis due to Staphylococcus aureus. Whereas rapid bactericidal activity is...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Oh, Jun Taek, Cassino, Cara, Schuch, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535547/
https://ncbi.nlm.nih.gov/pubmed/30936103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02616-18
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