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Postantibiotic and Sub-MIC Effects of Exebacase (Lysin CF-301) Enhance Antimicrobial Activity against Staphylococcus aureus

CF-301 (exebacase) is a recombinantly produced bacteriophage-derived lysin (cell wall hydrolase) and is the first agent of this class to enter clinical development in the United States for treating bacteremia including endocarditis due to Staphylococcus aureus. Whereas rapid bactericidal activity is...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Oh, Jun Taek, Cassino, Cara, Schuch, Raymond
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535547/
https://ncbi.nlm.nih.gov/pubmed/30936103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02616-18
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