1580. Colistin Potentiates the In Vitro Activity of Meropenem–Vaborbactam (M/V) Against Some, but not All KPC-producing Klebsiella pneumoniae (KPC-Kp)

BACKGROUND: M/V demonstrates potent in vitro activity against KPC-producing organisms. It is unclear whether the combination interacts synergistically with other active agents. METHODS: We tested isolates for responses to M/V alone (1 and 4x MIC; V fixed at 8 µg/mL), and in combination with colistin...

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Publicado no:Open Forum Infect Dis
Main Authors: Jones, Chelsea E, Kline, Ellen G, Nguyen, Minh-Hong, Clancy, Cornelius J, Shields, Ryan K
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6808712/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz360.1444
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