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Meropenem-Vaborbactam Resistance Selection, Resistance Prevention, and Molecular Mechanisms in Mutants of KPC-Producing Klebsiella pneumoniae

Vaborbactam (formerly RPX7009) is a new β-lactamase inhibitor based on a cyclic boronic acid pharmacophore with potent inhibitory activity against Klebsiella pneumoniae carbapenemases (KPC). It has been developed in combination with meropenem. The objective of these studies was to identify the conce...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Sun, Dongxu, Rubio-Aparicio, Debora, Nelson, Kirk, Dudley, Michael N., Lomovskaya, Olga
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700310/
https://ncbi.nlm.nih.gov/pubmed/29038260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01694-17
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