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Developing and Evaluating the HRM Technique for Identifying Cytochrome P450 2D6 Polymorphisms

BACKGROUND: Cytochrome P450 2D6 is one of the important enzymes involved in the metabolism of many widely used drugs. Genetic polymorphisms of CYP2D6 can affect its activity. Therefore, an efficient method for identifying CYP2D6 polymorphisms is clinically important. METHODS: We developed a high‐res...

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Vydáno v:J Clin Lab Anal
Hlavní autoři: Lu, Hsiu‐Chin, Chang, Ya‐Sian, Chang, Chun‐Chi, Lin, Ching‐Hsiung, Chang, Jan‐Gowth
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806731/
https://ncbi.nlm.nih.gov/pubmed/24798984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.21754
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