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Cancer Activation and Polymorphisms of Human Cytochrome P450 1B1

Human cytochrome P450 enzymes (P450s, CYPs) are major oxidative catalysts that metabolize various xenobiotic and endogenous compounds. Many carcinogens induce cancer only after metabolic activation and P450 enzymes play an important role in this phenomenon. P450 1B1 mediates bioactivation of many pr...

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Détails bibliographiques
Publié dans:Toxicol Res
Auteurs principaux: Chun, Young-Jin, Kim, Donghak
Format: Artigo
Langue:Inglês
Publié: Korean Society of Toxicology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843978/
https://ncbi.nlm.nih.gov/pubmed/27123158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5487/TR.2016.32.2.089
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