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Cancer Activation and Polymorphisms of Human Cytochrome P450 1B1

Human cytochrome P450 enzymes (P450s, CYPs) are major oxidative catalysts that metabolize various xenobiotic and endogenous compounds. Many carcinogens induce cancer only after metabolic activation and P450 enzymes play an important role in this phenomenon. P450 1B1 mediates bioactivation of many pr...

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Detalhes bibliográficos
Publicado no:Toxicol Res
Main Authors: Chun, Young-Jin, Kim, Donghak
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Toxicology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4843978/
https://ncbi.nlm.nih.gov/pubmed/27123158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5487/TR.2016.32.2.089
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