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Developing and Evaluating the HRM Technique for Identifying Cytochrome P450 2D6 Polymorphisms

BACKGROUND: Cytochrome P450 2D6 is one of the important enzymes involved in the metabolism of many widely used drugs. Genetic polymorphisms of CYP2D6 can affect its activity. Therefore, an efficient method for identifying CYP2D6 polymorphisms is clinically important. METHODS: We developed a high‐res...

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Detalhes bibliográficos
Publicado no:J Clin Lab Anal
Main Authors: Lu, Hsiu‐Chin, Chang, Ya‐Sian, Chang, Chun‐Chi, Lin, Ching‐Hsiung, Chang, Jan‐Gowth
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806731/
https://ncbi.nlm.nih.gov/pubmed/24798984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcla.21754
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