Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans

BACKGROUND: Epigenetic age acceleration, a measure of biological aging based on DNA methylation, is associated with cardiovascular mortality. However, little is known about its relationship with hypertensive target organ damage to the heart, kidneys, brain, and peripheral arteries. METHODS: We inves...

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Publicado en:BMC Med Genomics
Autores principales: Smith, Jennifer A., Raisky, Jeremy, Ratliff, Scott M., Liu, Jiaxuan, Kardia, Sharon L. R., Turner, Stephen T., Mosley, Thomas H., Zhao, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806502/
https://ncbi.nlm.nih.gov/pubmed/31640709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0585-5
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