Epigenetic loci for blood pressure are associated with hypertensive target organ damage in older African Americans from the genetic epidemiology network of Arteriopathy (GENOA) study

BACKGROUND: Hypertension is a major modifiable risk factor for arteriosclerosis that can lead to target organ damage (TOD) of heart, kidneys, and peripheral arteries. A recent epigenome-wide association study for blood pressure (BP) identified 13 CpG sites, but it is not known whether DNA methylatio...

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Vydáno v:BMC Med Genomics
Hlavní autoři: Kho, Minjung, Zhao, Wei, Ratliff, Scott M., Ammous, Farah, Mosley, Thomas H., Shang, Lulu, Kardia, Sharon L. R., Zhou, Xiang, Smith, Jennifer A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488710/
https://ncbi.nlm.nih.gov/pubmed/32917208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-00791-0
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