Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans

BACKGROUND: Epigenetic age acceleration, a measure of biological aging based on DNA methylation, is associated with cardiovascular mortality. However, little is known about its relationship with hypertensive target organ damage to the heart, kidneys, brain, and peripheral arteries. METHODS: We inves...

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Publicat a:BMC Med Genomics
Autors principals: Smith, Jennifer A., Raisky, Jeremy, Ratliff, Scott M., Liu, Jiaxuan, Kardia, Sharon L. R., Turner, Stephen T., Mosley, Thomas H., Zhao, Wei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806502/
https://ncbi.nlm.nih.gov/pubmed/31640709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0585-5
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