Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans

BACKGROUND: Epigenetic age acceleration, a measure of biological aging based on DNA methylation, is associated with cardiovascular mortality. However, little is known about its relationship with hypertensive target organ damage to the heart, kidneys, brain, and peripheral arteries. METHODS: We inves...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Smith, Jennifer A., Raisky, Jeremy, Ratliff, Scott M., Liu, Jiaxuan, Kardia, Sharon L. R., Turner, Stephen T., Mosley, Thomas H., Zhao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806502/
https://ncbi.nlm.nih.gov/pubmed/31640709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-019-0585-5
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