The mTOR kinase inhibitor rapamycin enhances the expression and release of pro-inflammatory cytokine interleukin 6 modulating the activation of human microglial cells

Emerging evidence suggests the potential use of rapamycin in treatment of several neurological disorders. The drug readily crosses the blood brain barrier and may exert direct immunomodulatory effects within the brain. Microglia are the main innate immune cells of the brain, thus critically involved...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EXCLI J
Main Authors: Cappoli, Natalia, Mezzogori, Daniele, Tabolacci, Elisabetta, Coletta, Isabella, Navarra, Pierluigi, Pani, Giovambattista, Dello Russo, Cinzia
Formato: Artigo
Idioma:Inglês
Publicado em: Leibniz Research Centre for Working Environment and Human Factors 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6806201/
https://ncbi.nlm.nih.gov/pubmed/31645839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2019-1715
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados