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WEE1 inhibition enhances sensitivity to hypoxia/reoxygenation in HeLa cells
Hypoxia/reoxygenation (H/R) treatment reportedly induces DNA damage response (DDR), including DNA double-strand break (DSB) repair and G2 arrest, resulting in reduction of clonogenic survival. Because WEE1 plays a key role in the G2/M checkpoint along with CHK1/2, we investigated the effect of WEE1...
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| Publicado no: | J Radiat Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6805980/ https://ncbi.nlm.nih.gov/pubmed/31347653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrz045 |
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