Fluctuation in radioresponse of HeLa cells during the cell cycle evaluated based on micronucleus frequency

In this study, we examined the fluctuation in radioresponse of HeLa cells during the cell cycle. For this purpose, we used HeLa cells expressing two types of fluorescent ubiquitination-based cell cycle indicators (Fucci), HeLa-Fucci (CA)2 and HeLa-Fucci (SA), and combined this approach with the micr...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Shimono, Hiroaki, Kaida, Atsushi, Homma, Hisao, Nojima, Hitomi, Onozato, Yusuke, Harada, Hiroyuki, Miura, Masahiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705701/
https://ncbi.nlm.nih.gov/pubmed/33257719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77969-0
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