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Effects of Chk1 inhibition on the temporal duration of radiation-induced G2 arrest in HeLa cells
Chk1 inhibitor acts as a potent radiosensitizer in p53-deficient tumor cells by abrogating the G2/M checkpoint. However, the effects of Chk1 inhibitor on the duration of G2 arrest have not been precisely analyzed. To address this issue, we utilized a cell-cycle visualization system, fluorescent ubiq...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4202296/ https://ncbi.nlm.nih.gov/pubmed/24894074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rru038 |
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