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WEE1 inhibition enhances sensitivity to hypoxia/reoxygenation in HeLa cells
Hypoxia/reoxygenation (H/R) treatment reportedly induces DNA damage response (DDR), including DNA double-strand break (DSB) repair and G2 arrest, resulting in reduction of clonogenic survival. Because WEE1 plays a key role in the G2/M checkpoint along with CHK1/2, we investigated the effect of WEE1...
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| Опубликовано в: : | J Radiat Res |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6805980/ https://ncbi.nlm.nih.gov/pubmed/31347653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrz045 |
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