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WEE1 inhibition enhances sensitivity to hypoxia/reoxygenation in HeLa cells
Hypoxia/reoxygenation (H/R) treatment reportedly induces DNA damage response (DDR), including DNA double-strand break (DSB) repair and G2 arrest, resulting in reduction of clonogenic survival. Because WEE1 plays a key role in the G2/M checkpoint along with CHK1/2, we investigated the effect of WEE1...
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| 出版年: | J Radiat Res |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6805980/ https://ncbi.nlm.nih.gov/pubmed/31347653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrz045 |
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