MLH1 deficiency leads to deregulated mitochondrial metabolism

The DNA mismatch repair (MMR) pathway is responsible for the repair of base–base mismatches and insertion/deletion loops that arise during DNA replication. MMR deficiency is currently estimated to be present in 15–17% of colorectal cancer cases and 30% of endometrial cancers. MLH1 is one of the key...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Dis
Asıl Yazarlar: Rashid, Sukaina, Freitas, Marta O., Cucchi, Danilo, Bridge, Gemma, Yao, Zhi, Gay, Laura, Williams, Marc, Wang, Jun, Suraweera, Nirosha, Silver, Andrew, McDonald, Stuart A. C., Chelala, Claude, Szabadkai, Gyorgy, Martin, Sarah A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805956/
https://ncbi.nlm.nih.gov/pubmed/31641109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2018-y
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