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Uncapping and Deregulation of Telomeres Lead to Detrimental Cellular Consequences in Yeast

Telomeres are the protein–nucleic acid structures at the ends of eukaryote chromosomes. Tandem repeats of telomeric DNA are templated by the RNA component (TER1) of the ribonucleoprotein telomerase. These repeats are bound by telomere binding proteins, which are thought to interact with other factor...

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Detalhes bibliográficos
Main Authors: Smith, Christopher D., Blackburn, Elizabeth H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2133106/
https://ncbi.nlm.nih.gov/pubmed/10209018
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