EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells

The EPHB4 receptor is implicated in the development of several epithelial tumors and is a promising therapeutic target, including in prostate tumors in which EPHB4 is overexpressed and promotes tumorigenicity. Here, we show that high expression of EPHB4 correlated with poor survival in prostate canc...

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Pubblicato in:Cell Death Dis
Autori principali: Sagar, Vinay, Vatapalli, Rajita, Lysy, Barbara, Pamarthy, Sahithi, Anker, Jonathan F., Rodriguez, Yara, Han, Huiying, Unno, Kenji, Stadler, Walter M., Catalona, William J., Hussain, Maha, Gill, Parkash S., Abdulkadir, Sarki A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805914/
https://ncbi.nlm.nih.gov/pubmed/31641103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2042-y
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