A cAbl-MRTF-A Feedback Loop Contributes to Hepatic Stellate Cell Activation

Trans-differentiation of quiescent hepatic stellate cells (HSC) to myofibroblasts is a hallmark event in liver fibrosis. Previous studies have led to the discovery that myocardin-related transcription factor A (MRTF-A) is a key regulator of HSC trans-differentiation or, activation. In the present st...

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Vydáno v:Front Cell Dev Biol
Hlavní autoři: Lu, Yunjie, Lv, Fangqiao, Kong, Ming, Chen, Xuyang, Duan, Yunfei, Chen, Xuemin, Sun, Donglin, Fang, Mingming, Xu, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805704/
https://ncbi.nlm.nih.gov/pubmed/31681772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00243
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