LncRNA HOTAIR contributes Taxol-resistance of hepatocellular carcinoma cells via activating AKT phosphorylation by down-regulating miR-34a

Drug resistance of Taxol leads to the treatment failure in hepatocellular carcinoma (HCC). LncRNA HOTAIR have drawn increasing attention in various diseases; its function and mechanism in Taxol-resistance in HCC remain unclear. In the present study, the two Taxol resistant HCC cell lines (HepG2/Taxo...

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Detalles Bibliográficos
Publicado en:Biosci Rep
Autores principales: Duan, Yunfei, Chen, Jing, Yang, Yu, Qu, Zhen, Lu, Yunjie, Sun, Donglin
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2020
Materias:
Cancer
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396434/
https://ncbi.nlm.nih.gov/pubmed/32700738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20201627
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