Functions of lncRNA HOTAIR in lung cancer

Long non-coding RNAs (lncRNAs) govern fundamental biochemical and cellular processes. lncRNA HOX transcript antisense RNA (HOTAIR) represses gene expression through recruitment of chromatin modifiers. The expression of HOTAIR is elevated in lung cancer and correlates with metastasis and poor prognos...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Hematol Oncol
Main Authors: Loewen, Gregory, Jayawickramarajah, Janarthanan, Zhuo, Ying, Shan, Bin
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266198/
https://ncbi.nlm.nih.gov/pubmed/25491133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-014-0090-4
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