LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation

BACKGROUND: MicroRNA-122 (miR-122), a pivotal liver-specific miRNA, is frequently repressed in hepatocellular carcinoma (HCC) and associated with poor prognosis. Long non-coding RNA (lncRNA) HOTAIR has been proved to function as an oncogene in multiple cancers including HCC. However, the relationshi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Cheng, Di, Deng, Junge, Zhang, Bin, He, Xiaoyu, Meng, Zhe, Li, Guolin, Ye, Huilin, Zheng, Shangyou, Wei, Lusheng, Deng, Xiaogeng, Chen, Rufu, Zhou, Jiajia
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197532/
https://ncbi.nlm.nih.gov/pubmed/30195653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.08.055
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados