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Allele-specific enhancer interaction at the Peg3 imprinted domain

The parental allele specificity of mammalian imprinted genes has been evolutionarily well conserved, although its functional constraints and associated mechanisms are not fully understood. In the current study, we generated a mouse mutant with switched active alleles driving the switch from paternal...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Joomyeong, Frey, Wesley D., Sharma, Kaustubh, Ghimire, Subash, Teruyama, Ryoichi, Stubbs, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804975/
https://ncbi.nlm.nih.gov/pubmed/31639176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224287
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