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Identification of an Evolutionarily Conserved Cis-Regulatory Element Controlling the Peg3 Imprinted Domain

The mammalian Peg3 domain harbors more than 20 evolutionarily conserved regions (ECRs) that are spread over the 250-kb genomic interval. The majority of these ECRs are marked with two histone modifications, H3K4me1 and H3K27ac, suggesting potential roles as distant regulatory elements for the transc...

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Detalhes bibliográficos
Main Authors: Thiaville, Michelle M., Kim, Hana, Frey, Wesley D., Kim, Joomyeong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769284/
https://ncbi.nlm.nih.gov/pubmed/24040411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075417
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