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Allele-specific enhancer interaction at the Peg3 imprinted domain

The parental allele specificity of mammalian imprinted genes has been evolutionarily well conserved, although its functional constraints and associated mechanisms are not fully understood. In the current study, we generated a mouse mutant with switched active alleles driving the switch from paternal...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Kim, Joomyeong, Frey, Wesley D., Sharma, Kaustubh, Ghimire, Subash, Teruyama, Ryoichi, Stubbs, Lisa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804975/
https://ncbi.nlm.nih.gov/pubmed/31639176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224287
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