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Allele-specific enhancer interaction at the Peg3 imprinted domain

The parental allele specificity of mammalian imprinted genes has been evolutionarily well conserved, although its functional constraints and associated mechanisms are not fully understood. In the current study, we generated a mouse mutant with switched active alleles driving the switch from paternal...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kim, Joomyeong, Frey, Wesley D., Sharma, Kaustubh, Ghimire, Subash, Teruyama, Ryoichi, Stubbs, Lisa
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804975/
https://ncbi.nlm.nih.gov/pubmed/31639176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224287
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