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Allele-specific enhancer interaction at the Peg3 imprinted domain

The parental allele specificity of mammalian imprinted genes has been evolutionarily well conserved, although its functional constraints and associated mechanisms are not fully understood. In the current study, we generated a mouse mutant with switched active alleles driving the switch from paternal...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Kim, Joomyeong, Frey, Wesley D., Sharma, Kaustubh, Ghimire, Subash, Teruyama, Ryoichi, Stubbs, Lisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804975/
https://ncbi.nlm.nih.gov/pubmed/31639176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224287
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