Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma

PURPOSE: High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-DH/TH) has a poor outcome after standard chemoimmunotherapy. We sought to understand the biologic underpinnings of HGBL-DH/TH with BCL2 rearrangements (HGBL-DH/TH-BCL2) and diffuse large B-cell lymphoma (DLBCL) mo...

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書誌詳細
出版年:J Clin Oncol
主要な著者: Ennishi, Daisuke, Jiang, Aixiang, Boyle, Merrill, Collinge, Brett, Grande, Bruno M., Ben-Neriah, Susana, Rushton, Christopher, Tang, Jeffrey, Thomas, Nicole, Slack, Graham W., Farinha, Pedro, Takata, Katsuyoshi, Miyata-Takata, Tomoko, Craig, Jeffrey, Mottok, Anja, Meissner, Barbara, Saberi, Saeed, Bashashati, Ali, Villa, Diego, Savage, Kerry J., Sehn, Laurie H., Kridel, Robert, Mungall, Andrew J., Marra, Marco A., Shah, Sohrab P., Steidl, Christian, Connors, Joseph M., Gascoyne, Randy D., Morin, Ryan D., Scott, David W.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Clinical Oncology 2019
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RAPID COMMUNICATIONS
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804880/
https://ncbi.nlm.nih.gov/pubmed/30523716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.18.01583
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