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The double-hit signature identifies double-hit diffuse large B-cell lymphoma with genetic events cryptic to FISH

High-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements (HGBL-DH/THs) include a group of diffuse large B-cell lymphomas (DLBCLs) with inferior outcomes after standard chemoimmunotherapy. We recently described a gene expression signature that identifies 27% of germinal center B-cell...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Hilton, Laura K., Tang, Jeffrey, Ben-Neriah, Susana, Alcaide, Miguel, Jiang, Aixiang, Grande, Bruno M., Rushton, Christopher K., Boyle, Merrill, Meissner, Barbara, Scott, David W., Morin, Ryan D.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839951/
https://ncbi.nlm.nih.gov/pubmed/31527075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002600
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