Загрузка...
Computationally Guided Design of Single-Chain Variable Fragment Improves Specificity of Chimeric Antigen Receptors
Chimeric antigen receptor (CAR)-T cell-based immunotherapy of malignant disease relies on the specificity and association constant of single-chain variable fragments (scFvs). The latter are synthesized from parent antibodies by fusing their light (V(L)) and heavy (V(H))-chain variable domains into a...
Сохранить в:
| Опубликовано в: : | Mol Ther Oncolytics |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Gene & Cell Therapy
2019
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6804740/ https://ncbi.nlm.nih.gov/pubmed/31650023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.08.008 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|