Comparative analysis of isoform-specific and non-selective histone deacetylase inhibitors in attenuating the intestinal damage after hemorrhagic shock

BACKGROUND: Isoform-specific histone deacetylase inhibitors (HDACIs) MC1568 and ACY1083 are comparable to the non-selective HDACI valproic acid (VPA) in improving survival in rodents undergoing lethal hemorrhage. However, the organ-specific properties of isoform-specific HDACIs have not been fully e...

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Foilsithe in:Trauma Surg Acute Care Open
Main Authors: Bhatti, Umar F, Williams, Aaron M, Kathawate, Ranganath G, Chang, Panpan, Zhou, Jing, Biesterveld, Ben E, Wu, Zhenyu, Dahl, Julia, Liu, Baoling, Li, Yongqing, Alam, Hasan B
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMJ Publishing Group 2019
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804098/
https://ncbi.nlm.nih.gov/pubmed/31692634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/tsaco-2019-000321
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