Differentially Methylated Super-Enhancers Regulate Target Gene Expression in Human Cancer

Current literature suggests that epigenetically regulated super-enhancers (SEs) are drivers of aberrant gene expression in cancers. Many tumor types are still missing chromatin data to define cancer-specific SEs and their role in carcinogenesis. In this work, we develop a simple pipeline, which can...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Flam, Emily L., Danilova, Ludmila, Kelley, Dylan Z., Stavrovskaya, Elena, Guo, Theresa, Considine, Michael, Qian, Jiang, Califano, Joseph A., Favorov, Alexander, Fertig, Elana J., Gaykalova, Daria A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803762/
https://ncbi.nlm.nih.gov/pubmed/31636280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51018-x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker