Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10(−/−) Mice

Fibrosis is a significant complication of intestinal disorders associated with microbial dysbiosis and pathobiont expansion, notably Crohn’s disease (CD). Mechanisms that favor fibrosis are not well understood, and therapeutic strategies are limited. Here we demonstrate that colitis-susceptible Il10...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Ellermann, Melissa, Gharaibeh, Raad Z., Fulbright, Laura, Dogan, Belgin, Moore, Lyndsey N., Broberg, Christopher A., Lopez, Lacey R., Rothemich, Aaron M., Herzog, Jeremy W., Rogala, Allison, Gordon, Ilyssa O., Rieder, Florian, Brouwer, Cory R., Simpson, Kenneth W., Jobin, Christian, Sartor, R. Balfour, Arthur, Janelle C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2019
Materias:
Host Response and Inflammation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803345/
https://ncbi.nlm.nih.gov/pubmed/31481410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00587-19
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