Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10(−/−) Mice

Fibrosis is a significant complication of intestinal disorders associated with microbial dysbiosis and pathobiont expansion, notably Crohn’s disease (CD). Mechanisms that favor fibrosis are not well understood, and therapeutic strategies are limited. Here we demonstrate that colitis-susceptible Il10...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Ellermann, Melissa, Gharaibeh, Raad Z., Fulbright, Laura, Dogan, Belgin, Moore, Lyndsey N., Broberg, Christopher A., Lopez, Lacey R., Rothemich, Aaron M., Herzog, Jeremy W., Rogala, Allison, Gordon, Ilyssa O., Rieder, Florian, Brouwer, Cory R., Simpson, Kenneth W., Jobin, Christian, Sartor, R. Balfour, Arthur, Janelle C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803345/
https://ncbi.nlm.nih.gov/pubmed/31481410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00587-19
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